Youth Violence Prevention Interventions (R01 - Clinical Trial Required) | RFA MD 24 002

Opportunity Information: Apply for RFA MD 24 002

The National Institute on Minority Health and Health Disparities (NIMHD), part of the National Institutes of Health (NIH), is offering an R01 research grant opportunity titled "Youth Violence Prevention Interventions (R01 - Clinical Trial Required)" under funding opportunity number RFA-MD-24-002 (CFDA 93.307). The purpose of the program is to fund rigorous research that develops and tests multilevel interventions aimed at preventing youth violence in communities and populations that experience health disparities. A central emphasis of this announcement is that proposed interventions should not only focus on individual behavior, but also incorporate strategies that address structural discrimination and other social determinants of health that contribute to violence risk and unequal outcomes. Because it is labeled "Clinical Trial Required," applicants are expected to include a clinical trial component, meaning the project should prospectively evaluate the effects of the intervention using a study design appropriate for testing efficacy or effectiveness.

The opportunity supports research in the broad health category and uses the grant funding instrument, specifically the NIH R01 mechanism, which typically supports substantial, multi-year projects that can test interventions at scale. The grant lists an award ceiling of $500,000, indicating the maximum funding level referenced in the source data for an individual award under this announcement. The posting shows an original closing date of October 2, 2023, and a creation date of June 29, 2023. While the listing notes "Expected Awards:" without a number, the key point is that this is a competitive NIH research funding opportunity where awards depend on application quality, responsiveness to the announcement, and available funds.

Eligibility is broad and includes a wide range of public and private entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments that are federally recognized; public housing authorities and Indian housing authorities; Native American tribal organizations that are not federally recognized tribal governments; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); for-profit organizations other than small businesses; and small businesses. The announcement also explicitly highlights additional eligible applicant types commonly emphasized in health equity funding, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI). It also notes that faith-based or community-based organizations, eligible federal government agencies, regional organizations, and U.S. territories or possessions may apply.

At the same time, there are clear restrictions related to foreign involvement. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply. In addition, non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. In practical terms, the applicant organization must be U.S.-based and the work cannot include foreign components as part of the proposed project structure.

Overall, this opportunity is designed for applicants who can bring together public health, clinical trial methods, and community-embedded intervention development to reduce youth violence while directly tackling upstream drivers like structural discrimination and other social determinants. Competitive projects will likely be those that clearly define the disparity population(s) of focus, specify the multilevel intervention strategy (for example, combining individual or family-level supports with school, community, housing, policy, or systems-level changes), and present a strong evaluation plan consistent with a clinical trial requirement.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Youth Violence Prevention Interventions (R01 - Clinical Trial Required)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.307.
• This funding opportunity was created on 2023-06-29.
• Applicants must submit their applications by 2023-10-02. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $500,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA MD 24 002

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