Opportunity Information: Apply for RFA CE 24 012
Rigorous Evaluation of Policy-Level Interventions to Prevent Overdose (R01) is a CDC Injury Center research grant opportunity that funds investigator-initiated studies focused on measuring what overdose-related policies actually do in real-world settings. The core aim is to generate strong, causal evidence on whether specific policies reduce drug use and overdose, while also examining whether those policies narrow or widen existing disparities in health and health care outcomes. This opportunity emphasizes that it is not enough to report overall changes in overdose indicators; applicants are expected to pay close attention to impacts on groups that experience a disproportionate overdose burden or who face elevated risk because of social determinants of health.
A central feature of the announcement is its focus on policy-level interventions. The policy being evaluated can be local, state, tribal, federal, or set at an organizational level such as within schools, health systems, or other institutions. The expectation is that the proposed study will rigorously evaluate the impact of the selected policy on at least two overdose-related outcomes. Examples of qualifying outcomes include nonfatal overdose, fatal overdose, substance use disorders, levels of substance use, and initiation of substance use among youth. In practice, this means projects should be designed to capture multiple dimensions of harm and risk rather than relying on a single indicator.
The CDC also places heavy weight on implementation, not just outcomes. Applicants are expected to study how the policy is implemented, how implementation differs across settings, and how those differences affect whether the policy achieves its intended effects. This includes examining barriers and facilitators to implementation and assessing how implementation quality or reach may vary for populations facing structural disadvantage. The rationale is that a policy that looks effective on paper may produce mixed or inequitable results if it is adopted unevenly, enforced inconsistently, or interacts with local service availability and social conditions.
From an administrative standpoint, this is a discretionary grant (R01 mechanism) under the Department of Health and Human Services, Centers for Disease Control and Prevention, and is associated with CFDA 93.136. The funding opportunity number is RFA CE 24 012. The maximum award amount listed is $350,000, and CDC anticipates making about 2 awards under this announcement. The opportunity was created on August 30, 2023, with an original application due date of December 1, 2023 (applications were due by 11:59 pm ET).
Eligibility is broad and includes many types of organizations that could reasonably carry out policy evaluation research. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those categories as specified); for-profit organizations other than small businesses; small businesses; and other entities as allowed under the additional eligibility language. Overall, the grant is structured to support rigorous, policy-relevant evaluation work that can guide decision-makers toward interventions that reduce overdose while avoiding unintended harms and preventing the worsening of inequities.Apply for RFA CE 24 012
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Rigorous Evaluation of Policy-Level Interventions to Prevent Overdose (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.136.
- This funding opportunity was created on Aug 30, 2023.
- Applicants must submit their applications by Dec 01, 2023 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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| Funding Opportunity |
|---|
| Research Grants to Identify Effective Community-Based Strategies for Overdose Prevention (R01) Apply for RFA CE 24 013 Funding Number: RFA CE 24 013 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $750,000 |
| Grants to Support New Investigators in Conducting Research Related to Understanding Drug Use and Overdose Risk and Protective Factors (K01) Apply for RFA CE 24 011 Funding Number: RFA CE 24 011 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $150,000 |
| Grants to Support New Investigators in Conducting Research Related to Preventing Interpersonal Violence Impacting Children and Youth Apply for RFA CE 24 029 Funding Number: RFA CE 24 029 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $150,000 |
| Research Grants for Preventing Violence and Violence Related Injury (R01) Apply for RFA CE 24 030 Funding Number: RFA CE 24 030 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $400,000 |
| Global Health Security Apply for SSN 621 23 HO 00001 Funding Number: SSN 621 23 HO 00001 Agency: Agency for International Development, Tanzania USAID-Dar es Salaam Category: Health Funding Amount: $20,000,000 |
| Local Health Solutions (LHS) Apply for 72066923RFA00004 Funding Number: 72066923RFA00004 Agency: Agency for International Development, Liberia USAID-Monrovia Category: Health Funding Amount: $24,000,000 |
| Rigorous Evaluation of Policies for their Impacts on the Primary Prevention of Multiple Forms of Violence Apply for RFA CE 24 034 Funding Number: RFA CE 24 034 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $350,000 |
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| Rape Prevention and Education Apply for CDC RFA CE 24 0027 Funding Number: CDC RFA CE 24 0027 Agency: Department of Health and Human Services, Centers for Disease Control - NCIPC Category: Health Funding Amount: $4,200,000 |
| Supporting Healthy Start Performance Project Apply for HRSA 24 038 Funding Number: HRSA 24 038 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $3,500,000 |
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